I am happy to had chosen the Paragon path and saved 50000 platinum in skin treatment.

Renegade options are fun, but they aren't without disadvantages. I truly expect the big renegade decisions (like how to deal with the Rachni) to somehow reflect negatively in the last game, but Bioware is free to prove me wrong.

Of course, if leaving the universe in utter chaos is what you want, I guess renegade is really the way to go.

You still get a terrible skin rash for it though.