To answer honestly, I'd probably won't change the characters, different from TF2 the characters in DOTA are specific people so changing them would not work in most cases... except a certain one I will definitely do for sure. Can you guess which one?

But the keyword here is "probably". I can see myself doing it for kicks and giggles because I can.

p.s. Kunkka and Tidehunter most probably would remain like they are, which is a pity because Tidehunter is totally tsundere for Kunkka.